Chembl2165137


SMILES Clc1cccc(C2CCN(CCCCOc3ccc4scnc4c3)CC2)c1Cl
InChIKey DXXXGJIMFKZHRL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 434.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 9.22 9.22 9.22 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 9.22 9.22 9.22 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.22 9.22 9.22 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.22 9.22 9.22 ChEMBL
D2 DRD2 Human Dopamine A pEC50 7.09 7.29 7.68 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.38 7.38 7.38 ChEMBL