CHEMBL2159490


SMILES CC(C)c1ccccc1OCCN1CC[C@H](NS(=O)(=O)c2ccc(Cl)s2)C1
InChIKey WIMXOLDVKJDYQI-HNNXBMFYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 428.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.55 7.55 7.55 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.27 6.27 6.27 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.05 7.05 7.05 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.6 7.6 7.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database