Ligand Data

Ligand

id 81909
Name CHEMBL2158498
SMILES COc1cc([C@H]2[C@](NC(=O)c3ccc(NC(=O)C(C)NC(=O)OC(C)(C)C)cc3)(C(=O)O)[C@@H](c3ccc(OC(=O)c4cccs4)c(OC)c3)[C@]2(NC(=O)c2ccc(NC(=O)C(C)NC(=O)OC(C)(C)C)cc2)C(=O)O)ccc1OC(=O)c1cccs1
InChIKey HFYBRENLMFCHNB-SQPNUHFPSA-N
Type small-molecule
External Links

Structure

Properties

Hydrogen bond acceptors 18
Hydrogen bond donors 8
Rotatable bonds 20
Molecular weight 1218.4


Bioactivity

Receptor Affinity (nM) Potency (nM)
GTP Uniprot Species Family Class Min Avg Max Min Avg Max
GLP-1 GLP1R Rat Glucagon B1 (Secretin) 900 900 900