Chembl2179659


SMILES O=C(CCc1ccccc1)O[C@@]12Cc3cc(-c4ccc(Cl)cc4)cnc3[C@@H]3Oc4c(O)ccc5c4[C@@]31CCN(CC1CC1)[C@@H]2C5
InChIKey WTQCCWURXMRMMY-GBYFWFCKSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 618.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.38 8.38 8.38 ChEMBL
κ OPRK Human Opioid A pEC50 7.89 7.89 7.89 ChEMBL
κ OPRK Human Opioid A pKi 7.92 7.92 7.92 ChEMBL
μ OPRM Human Opioid A pKi 8.59 8.59 8.59 ChEMBL