CHEMBL2205616


SMILES O=C(Nc1sc2c(c1C(=O)N1CCCCC1)CCOC2)c1ccccc1OC(F)(F)F
InChIKey BKNFVLJTRIWUGZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 454.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Rat Cannabinoid A pKi 5.67 5.67 5.67 ChEMBL
CB1 CNR1 Rat Cannabinoid A pKi 4.65 4.65 4.65 ChEMBL
CB2 CNR2 Human Cannabinoid A pKi 6.46 6.46 6.46 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 4.71 4.71 4.71 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pEC50 8.02 8.02 8.02 ChEMBL
CB1 CNR1 Human Cannabinoid A pEC50 6.03 6.03 6.03 ChEMBL