CHEMBL220274


SMILES O=C1c2c(cccc2C(F)(F)F)C2CNCCN12
InChIKey MYJCTHLPBPJBRB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 256.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.6 6.6 6.6 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.72 7.72 7.72 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.96 6.96 6.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 6.72 6.72 6.72 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.62 7.62 7.62 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.88 6.88 6.88 ChEMBL