CHEMBL2207642


SMILES COc1ccccc1N1CCN(Cc2cc(CN3CCN(c4ccc(Cl)cc4)CC3)c3cccccc2-3)CC1
InChIKey VDCBDIRJDJYCIZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 540.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.8 5.8 5.8 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.96 5.96 5.96 ChEMBL
H2 HRH2 Human Histamine A pKi 6.34 6.34 6.34 ChEMBL
H1 HRH1 Human Histamine A pKi 6.31 6.31 6.31 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.22 8.22 8.22 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.07 7.07 7.07 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.8 6.91 7.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database