CHEMBL2205591


SMILES O=C(Nc1sc2c(c1C(=O)N1CC(F)(F)C1)CCOC2)c1ccccc1C(F)(F)F
InChIKey HFQXITZIZRQNOH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 446.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Rat Cannabinoid A pKi 6.23 6.23 6.23 ChEMBL
CB2 CNR2 Human Cannabinoid A pKi 7.09 7.09 7.09 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 5.14 5.14 5.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pEC50 8.6 8.6 8.6 ChEMBL
CB1 CNR1 Human Cannabinoid A pEC50 6.53 6.53 6.53 ChEMBL