CHEMBL2208347


SMILES C[C@H]1[C@H]2Cc3ccc(C(=O)NCCc4ccc(-c5ccc(O)cc5)cc4)cc3[C@]1(C)CCN2CC1CC1
InChIKey FTRDSYLIWZRYMR-OAXZOYPSSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 494.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 9.11 9.11 9.11 ChEMBL
κ OPRK Human Opioid A pKi 9.44 9.44 9.44 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 9.51 9.51 9.51 ChEMBL
κ OPRK Human Opioid A pEC50 9.59 9.59 9.59 ChEMBL
μ OPRM Human Opioid A pIC50 8.35 8.35 8.35 ChEMBL
μ OPRM Human Opioid A pEC50 9.3 9.3 9.3 ChEMBL