trihexyphenidyl [8402]



trihexyphenidyl


SMILES OC(CCN1CCCCC1)(c1ccccc1)C1CCCCC1
InChIKey HWHLPVGTWGOCJO-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Log P 4.330
Molecular weight (Da) 301.2
Stereochemistry info unspecified

Database connections

Model (Boltz2) M1
Ligand site mutations M1 M3
GPCRdb related ligands

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

trihexyphenidyl


Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 0
Phase II 1
Phase III 0
Phase IV 1

Database connections

Model (Boltz2) M1
Ligand site mutations M1 M3

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score