Chembl222762


SMILES Oc1ccc2c3c1O[C@H]1c4c(c5c(n4CCc4ccccc4)CCCC5)C[C@@]4(O)C(C2)N(CC2CC2)CC[C@]314
InChIKey UTELNNIXGGIXPC-PJRPWTOZSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 522.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.74 8.74 8.74 ChEMBL
δ OPRD Human Opioid A pEC50 6.96 6.96 6.96 ChEMBL
κ OPRK Human Opioid A pKi 8.05 8.05 8.05 ChEMBL
κ OPRK Human Opioid A pEC50 7.86 7.86 7.86 ChEMBL
μ OPRM Human Opioid A pKi 8.13 8.13 8.13 ChEMBL