CHEMBL2207636


SMILES COc1ccccc1N1CCN(Cc2cc(C#N)c3cccccc2-3)CC1
InChIKey LQGNDHYNCHVOGU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 357.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 6.39 6.39 6.39 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.62 8.62 8.62 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.28 6.28 6.28 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.41 7.75 8.08 ChEMBL
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.42 6.42 6.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database