Ligand Data
Ligand
| Name | CHEMBL220274 |
| SMILES | O=C1c2c(cccc2C(F)(F)F)C2CNCCN12 |
| InChIKey | MYJCTHLPBPJBRB-UHFFFAOYSA-N |
| Type | small-molecule |
| External Links |
Structure
Properties
| Hydrogen bond acceptors | 2 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 0 |
| Molecular weight | 256.1 |
Bioactivity
| Receptor | Affinity (nM) | Potency (nM) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Min | Avg | Max | Min | Avg | Max |
| 5-HT2B | 5HT2B | Human | 5-Hydroxytryptamine | A (Rhodopsin) | 192 | 192 | 192 | |||
| 5-HT2C | 5HT2C | Human | 5-Hydroxytryptamine | A (Rhodopsin) | 24.0 | 24.0 | 24.0 | |||
| 5-HT2A | 5HT2A | Human | 5-Hydroxytryptamine | A (Rhodopsin) | 131 | 131 | 131 | |||