Ligand Data

Ligand

id 84151
Name CHEMBL220274
SMILES O=C1c2c(cccc2C(F)(F)F)C2CNCCN12
InChIKey MYJCTHLPBPJBRB-UHFFFAOYSA-N
Type small-molecule
External Links

Structure

Properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight 256.1


Bioactivity

Receptor Affinity (nM) Potency (nM)
GTP Uniprot Species Family Class Min Avg Max Min Avg Max
5-HT2B 5HT2B Human 5-Hydroxytryptamine A (Rhodopsin) 192 192 192
5-HT2C 5HT2C Human 5-Hydroxytryptamine A (Rhodopsin) 24.0 24.0 24.0
5-HT2A 5HT2A Human 5-Hydroxytryptamine A (Rhodopsin) 131 131 131