CHEMBL222188


SMILES O=C(CCCCCN1CCN(c2ccccc2)CC1)NC1CCCc2ccccc21
InChIKey OPNMLXKOFJADTH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 405.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.18 7.18 7.18 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.89 6.89 6.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.0 6.0 6.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.0 6.0 6.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Guinea pig 5-Hydroxytryptamine A pEC50 5.1 5.1 5.1 ChEMBL