FK-788


SMILES OC(=O)COc1cccc2c1CC[C@](C2)(O)COC(=O)N(c1ccccc1)c1ccccc1
InChIKey UZJAIYJXBYWENR-AREMUKBSSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 447.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
IP PI2R Human Prostanoid A pKi 8.05 8.05 8.05 Guide to Pharmacology
DP1 PD2R Human Prostanoid A pKi 5.64 5.64 5.64 ChEMBL
EP1 PE2R1 Human Prostanoid A pKi 5.02 5.02 5.02 ChEMBL
EP3 PE2R3 Human Prostanoid A pKi 5.09 5.09 5.09 ChEMBL
IP PI2R Human Prostanoid A pKi 8.05 8.05 8.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database