TRV027 [8432]



TRV027


SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O
InChIKey XIEWFECSPPTVQN-KMIMAYJXSA-N
Sequence XRVYIHPA
HELM PEPTIDE1{[Sar].R.V.Y.I.H.P.[dA]}$$$$

Chemical Properties

Hydrogen bond acceptors 12
Hydrogen bond donors 12
Rotatable bonds 26
Log P -2.120
Molecular weight (Da) 925.5
Stereochemistry info partial

Database connections

Model (AF2) AT1
GPCRdb related ligands

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

TRV027


Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 0
Phase II 0
Phase III 0
Phase IV 0

Database connections

Model (AF2) AT1

Compound is not listed as a drug.