fluparoxan


SMILES Fc1cccc2c1O[C@H]1CNC[C@@H]1O2
InChIKey XSOUHEXVEOQRKJ-IUCAKERBSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 195.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pKi 8.1 8.13 8.2 PDSP Ki database
α2B ADA2B Human Adrenoceptors A pKi 8.9 8.9 8.9 PDSP Ki database
α2C ADA2C Human Adrenoceptors A pKi 8.8 8.8 8.8 PDSP Ki database
α2A ADA2A Rat Adrenoceptors A pKi 8.9 8.9 8.9 PDSP Ki database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 PDSP Ki database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 PDSP Ki database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 PDSP Ki database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 PDSP Ki database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 PDSP Ki database
α1B ADA1B Human Adrenoceptors A pKi 6.0 6.0 6.0 PDSP Ki database
α1D ADA1D Human Adrenoceptors A pKi 6.3 6.6 6.9 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.0 6.0 6.0 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.0 6.0 6.0 PDSP Ki database
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 PDSP Ki database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 PDSP Ki database
5-HT1B 5HT1B Guinea pig 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 PDSP Ki database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 Guide to Pharmacology
D2 DRD2 Rat Dopamine A pKi 5.5 5.5 5.5 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database