CHEMBL223468


SMILES CCc1ccc2c(c1OC)C(=O)N1CCNC[C@@H]21
InChIKey ZWKILPBYPRWWLP-NSHDSACASA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 246.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.37 7.37 7.37 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.75 7.75 7.75 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.43 7.43 7.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.91 6.91 6.91 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 8.1 8.1 8.1 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 8.85 8.85 8.85 ChEMBL