CHEMBL210283


SMILES COc1ccccc1N1CCN(Cc2cn3cc(C)cc(C#N)c3n2)CC1
InChIKey VXHLHYPOHKQMNB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 361.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 4.4 4.4 4.4 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.89 8.89 8.89 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.46 5.46 5.46 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.38 5.47 5.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database