CILANSETRON


SMILES Cc1nccn1C[C@H]1CCc2c(c3cccc4c3n2CCC4)C1=O
InChIKey NCNFDKWULDWJDS-OAHLLOKOSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 319.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Rat Histamine A pKi 5.19 5.19 5.19 ChEMBL
5-HT4 5HT4R Rat 5-Hydroxytryptamine A pKi 6.02 6.02 6.02 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 6.04 6.04 6.04 ChEMBL
μ OPRM Rat Opioid A pKi 5.07 5.07 5.07 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 5.31 5.31 5.31 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database