CHEMBL2109988


SMILES Cc1ccc(N2CCN(CC3CC3c3ccccc3)CC2)c(C)c1
InChIKey PQFHVDFLICEIKC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 320.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 6.03 6.2 6.29 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 8.15 8.15 8.15 ChEMBL
D2 DRD2 Human Dopamine A pIC50 7.22 7.22 7.22 ChEMBL