CHEMBL228857


SMILES COc1ccccc1C(c1ccccc1)N1CCC(O)(c2ccccc2)CC1
InChIKey DFUCPZAAMSSVDD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 373.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 7.55 7.55 7.55 ChEMBL
δ OPRD Human Opioid A pKi 6.01 6.01 6.01 ChEMBL
κ OPRK Human Opioid A pKi 6.29 6.29 6.29 ChEMBL
NOP OPRX Human Opioid A pKi 9.0 9.0 9.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 7.58 7.58 7.58 ChEMBL