CHEMBL229440


SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1C/C=C/C[C@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O
InChIKey VNZCTJLIVONUDE-KLGXLVMCSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 7
Rotatable bonds 7
Molecular weight (Da) 551.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 7.13 7.13 7.13 ChEMBL
μ OPRM Rat Opioid A pKi 8.89 8.89 8.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 9.06 9.06 9.06 ChEMBL
μ OPRM Human Opioid A pEC50 8.58 8.58 8.58 ChEMBL
δ OPRD Mouse Opioid A pIC50 9.12 9.12 9.12 ChEMBL