CHEMBL231057


SMILES COc1ccccc1N1CCN(CCCCOc2ccc(-c3cn4cccc(C)c4n3)cc2)CC1
InChIKey DZWGDUHDXDFOQC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 470.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 6.8 6.8 6.8 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.8 6.8 6.8 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.41 6.41 6.41 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.42 6.42 6.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database