angiotensin-(1-7) (Human) [862]



angiotensin-(1-7) (Human)


SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)O
InChIKey PVHLMTREZMEJCG-GDTLVBQBSA-N
Sequence DRVYIHP
HELM PEPTIDE1{D.R.V.Y.I.H.P}$$$$

Chemical Properties

Hydrogen bond acceptors 12
Hydrogen bond donors 12
Rotatable bonds 25
Log P -2.042
Molecular weight (Da) 898.5
Stereochemistry info partial

Database connections

Model (AF2) AT2
Model (Boltz2) MAS1
GPCRdb related ligands

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

angiotensin-(1-7) (Human)


Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug Yes

Distribution across phases (no. indications)

Phase I 6
Phase II 2
Phase III 0
Phase IV 0

Database connections

Model (AF2) AT2
Model (Boltz2) MAS1

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score