CHEMBL231648


SMILES CN1CCc2cc(Cl)c(NS(=O)(=O)c3ccc(-c4ccc(Cl)cc4)cc3)cc2CC1
InChIKey CUDIFALFXGTJEV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 460.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.3 7.3 7.3 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.4 7.4 7.4 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.5 7.5 7.5 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.6 8.6 8.6 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.4 7.4 7.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database