Chembl2338752


SMILES CO[C@]12CC[C@@]3(C[C@@H]1[C@](C)(O)Cc1ccccc1)[C@H]1Cc4ccc(O)c5c4[C@@]3(CCN1CC1CC1)[C@H]2O5
InChIKey AGFBWCLIEGGCOZ-PPMCTTEPSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 501.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pEC50 8.89 8.89 8.89 ChEMBL
μ OPRM Rat Opioid A pKi 9.82 9.82 9.82 ChEMBL
κ OPRK Human Opioid A pEC50 10.15 10.15 10.15 ChEMBL
κ OPRK Human Opioid A pKi 10.09 10.09 10.09 ChEMBL