Chembl2338753


SMILES CO[C@]12CC[C@@]3(C[C@@H]1[C@](C)(O)CCc1ccccc1)[C@H]1Cc4ccc(O)c5c4[C@@]3(CCN1CC1CC1)[C@H]2O5
InChIKey GJCIZLCOLGPOTH-VTRXWXBFSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 515.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pEC50 8.31 8.31 8.31 ChEMBL
μ OPRM Rat Opioid A pKi 9.49 9.49 9.49 ChEMBL
κ OPRK Human Opioid A pEC50 10.8 10.8 10.8 ChEMBL
κ OPRK Human Opioid A pKi 10.19 10.19 10.19 ChEMBL