CHEMBL2146812


SMILES CN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2nccnc2c1=O
InChIKey DGZLHXBKGBELTQ-OAHLLOKOSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 369.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.6 6.6 6.6 ChEMBL
H1 HRH1 Human Histamine A pKi 8.89 8.89 8.89 ChEMBL
H1 HRH1 Human Histamine A pKd 8.4 8.4 8.4 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.4 6.4 6.4 ChEMBL
H3 HRH3 Human Histamine A pKi 6.2 6.2 6.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database