CHEMBL1096827


SMILES CC(=O)N1C[C@@H](Oc2cccc(F)c2)C[C@@H]1C(=O)N1CCCN(C2CCC2)CC1
InChIKey USNNNBJEPXKOFF-LEWJYISDSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 403.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 7.57 7.57 7.57 ChEMBL
H3 HRH3 Rat Histamine A pKd 8.22 8.22 8.22 ChEMBL
H3 HRH3 Human Histamine A pKi 8.8 8.8 8.8 ChEMBL
H3 HRH3 Human Histamine A pKd 9.5 9.5 9.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database