CHEMBL2159481


SMILES O=S(=O)(NC1CCN(CCOc2ccccc2-c2ccccc2)C1)c1ccc(F)c(F)c1
InChIKey AJRQMVCEFKRUBB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 458.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.49 6.49 6.49 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.04 7.04 7.04 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.62 7.62 7.62 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.15 8.15 8.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database