CFMTI


SMILES O=C1N(Cc2c1ccc(c2)c1nnn(c1C)c1cccnc1F)C1CC1
InChIKey XZBFQWRAIYRPPZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 349.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 8.59 8.59 8.59 Guide to Pharmacology
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 5.27 5.27 5.27 ChEMBL
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 8.46 8.46 8.46 ChEMBL