Chembl236663

Chemical Properties

SMILES Cc1cccc(C)c1Cc1[nH]c(=O)c(CCCCNC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C
Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 10
Molecular weight 490.3

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey PFRMPRUILAXAIG-VWLOTQADSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pKd 6.61 6.61 6.61 ChEMBL
δ OPRD Human Opioid A pKi 8.28 8.28 8.28 ChEMBL
μ OPRM Human Opioid A pKi 9.18 9.18 9.18 ChEMBL