CHEMBL2164350


SMILES O=C(C1CCCCC1)N(CCN1CCN(c2ccccc2)CC1)c1ccccn1
InChIKey QJFWBEXGRNKZIY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 392.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 5.98 5.98 5.98 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.7 6.7 6.7 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.02 6.31 6.61 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.23 6.23 6.23 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.49 6.49 6.49 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.75 6.75 6.75 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.73 8.82 8.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database