CHEMBL2365703


SMILES CN1C(=O)c2c(cccc2C(F)(F)F)[C@H]2CNC[C@@H]21
InChIKey MVQAXNPRALNHQX-SCZZXKLOSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 270.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.62 7.62 7.62 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.34 7.34 7.34 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.1 7.1 7.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 7.5 7.5 7.5 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 8.48 8.48 8.48 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 7.05 7.05 7.05 ChEMBL