CHEMBL236675


SMILES CNCc1cc(C#CCCN2CCOCC2)ccc1Oc1ccc(C(F)(F)F)cc1
InChIKey RVSCXYLNWULPGJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 418.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pKd 7.9 7.9 7.9 ChEMBL
H3 HRH3 Human Histamine A pKi 8.14 8.14 8.14 ChEMBL
H3 HRH3 Human Histamine A pKi 8.14 8.14 8.14 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database