CHEMBL2365359


SMILES Cc1ccc2c(c1Cl)C(=O)N[C@H]1CNC[C@H]21
InChIKey OQRKNKXYAJHBOA-BDAKNGLRSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 0
Molecular weight (Da) 236.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.4 8.4 8.4 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.31 8.31 8.31 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 8.66 8.66 8.66 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 7.68 7.68 7.68 ChEMBL