CHEMBL218115


SMILES CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccco1
InChIKey JBJWLRHFBRZPOP-GFCCVEGCSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 7
Molecular weight (Da) 383.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CXCR1 CXCR1 Human Chemokine A pKd 8.41 8.41 8.41 ChEMBL
CXCR2 CXCR2 Human Chemokine A pKd 10.31 10.31 10.31 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CXCR1 CXCR1 Human Chemokine A pIC50 7.58 7.58 7.58 ChEMBL
CXCR2 CXCR2 Human Chemokine A pIC50 8.42 8.42 8.42 ChEMBL