CHEMBL2181187


SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1
InChIKey OLINRUQQUFMPJJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 364.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 7.77 7.77 7.77 ChEMBL
5-HT4 5HT4R Guinea pig 5-Hydroxytryptamine A pKi 7.46 7.46 7.46 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.59 5.59 5.59 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.46 5.46 5.46 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.53 7.53 7.53 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.22 5.22 5.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pEC50 7.1 7.1 7.1 ChEMBL