Chembl2387709


SMILES CCCN(CCN1CCN(c2ccccc2)CC1)[C@@H]1CCc2ccc(N)cc2C1
InChIKey FJXRWQLSUYHSFX-RUZDIDTESA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 392.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.7 7.7 7.7 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.22 6.22 6.22 ChEMBL
D3 DRD3 Human Dopamine A pEC50 7.52 7.52 7.52 ChEMBL
D2 DRD2 Human Dopamine A pEC50 6.75 6.75 6.75 ChEMBL