pimozide


SMILES Fc1ccc(cc1)C(c1ccc(cc1)F)CCCN1CCC(CC1)n1c(=O)[nH]c2c1cccc2
InChIKey YVUQSNJEYSNKRX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 461.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Ligand site mutations D2

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
P2Y2 P2RY2 Human P2Y A pEC50 7.3 7.3 7.3 Guide to Pharmacology
P2Y6 P2RY6 Human P2Y A pEC50 5.82 5.82 5.82 ChEMBL
P2Y2 P2RY2 Human P2Y A pEC50 7.3 7.42 7.46 ChEMBL
P2Y4 P2RY4 Human P2Y A pEC50 5.75 6.28 6.46 ChEMBL