CHEMBL109912


SMILES CNc1cc(OC)c(C(=O)N[C@H]2CCN(Cc3ccccc3)C[C@@H]2C)cc1Cl
InChIKey OJELFRWBMVFUDD-KXBFYZLASA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 401.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.09 5.22 5.36 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.33 8.57 8.8 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.29 7.09 7.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.27 7.74 8.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database