ADL5747


SMILES CCN(C(=O)c1ccc(c(c1)O)C1=CC2(CCNCC2)Oc2c1cccc2)CC
InChIKey ALGHKWSXJUQNJJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 392.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.57 8.57 8.57 Guide to Pharmacology
μ OPRM Human Opioid A pKi 7.74 7.74 7.74 Guide to Pharmacology
δ OPRD Human Opioid A pKi 8.57 8.57 8.57 ChEMBL
κ OPRK Human Opioid A pKi 7.6 7.6 7.6 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 7.03 7.03 7.03 ChEMBL