ADL5859


SMILES CCN(C(=O)c1ccc(cc1)C1=CC2(CCNCC2)Oc2c1c(O)ccc2)CC
InChIKey OPIKUXLJQFYMSC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 392.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 7.43 7.43 7.43 Guide to Pharmacology
μ OPRM Human Opioid A pKi 7.49 7.49 7.49 Guide to Pharmacology
δ OPRD Human Opioid A pKi 9.08 9.08 9.08 ChEMBL
δ OPRD Human Opioid A pKi 9.08 9.08 9.08 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 7.7 7.7 7.7 ChEMBL