GPCRdb

CHEMBL2381649

Agent/drug
Bioactivity

CHEMBL2381649

SMILES	CC(=O)N[C@H]1C[C@@](N)(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@H]12
InChIKey	APZIMAYYQKOWFP-ONZQZHTRSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	4
Rotatable bonds	3
Molecular weight (Da)	242.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

mGlu₂	GRM2	Human	Metabotropic glutamate	C	pKi	6.05	6.05	6.05	ChEMBL
mGlu₃	GRM3	Human	Metabotropic glutamate	C	pKi	6.75	6.75	6.75	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

mGlu₂	GRM2	Human	Metabotropic glutamate	C	pEC50	6.59	6.59	6.59	ChEMBL
mGlu₃	GRM3	Human	Metabotropic glutamate	C	pEC50	6.71	6.71	6.71	ChEMBL
mGlu₆	GRM6	Human	Metabotropic glutamate	C	pEC50	6.15	6.15	6.15	ChEMBL
mGlu₈	GRM8	Human	Metabotropic glutamate	C	pEC50	5.37	5.37	5.37	ChEMBL

Showing 1 to 4 of 4 entries

CHEMBL2381649

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.