L-817,818


SMILES NCCCC[C@@H](C(=O)OC[C@@H](N)C)NC(=O)Cc1c([nH]c2c1ccc1c2cccc1)c1ccc2c(c1)cccc2
InChIKey NFVRGDRCCNEGBS-LGGPFLRQSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 11
Molecular weight (Da) 536.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SST1 SSR1 Human Somatostatin A pKi 8.5 8.5 8.5 Guide to Pharmacology
SST5 SSR5 Human Somatostatin A pKi 9.4 9.4 9.4 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SST5 SSR5 Human Somatostatin A pIC50 9.4 9.4 9.4 ChEMBL