CHEMBL2392349


SMILES COc1ccccc1N1CCN(CCCCCN2Cc3ccc4ccccc4c3C2=O)CC1
InChIKey YIIWKHZEONNJTQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 443.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.8 8.8 8.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 7.21 7.21 7.21 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 7.37 7.37 7.37 ChEMBL
D4 DRD4 Human Dopamine A pIC50 7.19 7.19 7.19 ChEMBL
D3 DRD3 Human Dopamine A pIC50 7.62 7.62 7.62 ChEMBL
D2 DRD2 Human Dopamine A pIC50 8.46 8.46 8.46 ChEMBL