CHEMBL2207641


SMILES COc1ccccc1N1CCN(Cc2cc(CN3CCN(c4ccccc4OC)CC3)c3cccccc2-3)CC1
InChIKey HVGNYVOUQOKFLU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 536.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.25 6.25 6.25 ChEMBL
D1 DRD1 Pig Dopamine A pKi 6.13 6.13 6.13 ChEMBL
H2 HRH2 Human Histamine A pKi 6.28 6.28 6.28 ChEMBL
H1 HRH1 Human Histamine A pKi 6.0 6.0 6.0 ChEMBL
D4 DRD4 Human Dopamine A pKi 9.1 9.1 9.1 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.48 7.48 7.48 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.47 7.62 7.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database