CHEMBL2207643


SMILES COc1ccccc1N1CCN(Cc2ccc3cccccc2-3)CC1
InChIKey MNVDCQLMHFFYCU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 332.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 7.04 7.04 7.04 ChEMBL
D1 DRD1 Pig Dopamine A pKi 6.3 6.3 6.3 ChEMBL
D4 DRD4 Human Dopamine A pKi 9.4 9.4 9.4 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.48 7.53 7.62 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.08 7.08 7.09 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 8.43 8.43 8.43 ChEMBL