CHEMBL2392174


SMILES COc1ccc(C(=O)Nc2cc(Br)cc3c(=O)cc(C(=O)O)oc23)cc1
InChIKey TZKQFDIFVZAYER-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 417.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR35 GPR35 Human A orphans A pKd 6.94 7.93 8.28 ChEMBL
GPR35 GPR35 Human A orphans A pKi 8.29 8.29 8.29 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR35 Q33BM1 Rat A orphans A pEC50 5.85 5.85 5.85 ChEMBL
GPR55 GPR55 Human GPR18, GPR55 and GPR119 A pIC50 4.66 4.66 4.66 ChEMBL
GPR35 GPR35 Human A orphans A pEC50 7.66 7.86 7.92 ChEMBL