CHEMBL2397877


SMILES O=C1c2cc(Cl)ccc2C[C@@H]2CNCCN12
InChIKey UMHOHNRDOOBXDJ-SNVBAGLBSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 236.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.27 7.27 7.27 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.52 7.52 7.52 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.07 7.07 7.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 8.05 8.05 8.05 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 8.0 8.0 8.0 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 7.01 7.01 7.01 ChEMBL